The Pritzker prize-winner, who opened her Thirty Years in Architecture retrospective show at the Guggenheim, New York, last weekend, saw off some of the world's biggest architectural names to land the multimillion-pound Business Bay project.
The finalists included radical Los Angeles-based Morphosis Architects; New York's RUR Architecture; and Rem Koolhaas' Office of Metropolitan Architects.
Hadid's scheme, which features three 'intertwined towers', was chosen because it captured 'the essence and global relevance of Business Bay.'
The ever-expanding development has been already dubbed 'a city within a city' and has become a favourite spot for a raft of multinational companies to set up their headquarters.
It is understood Hadid's designs will be officially unveiled in New York later this week.
The contest was organised by developer Dubai Properties - an arm of business giant Dubai Holding.