Speaking at the Thames Gateway Forum, the prime minister also announced plans to make the Thames Gateway the UK's first-ever eco region to include a new Eco-Quarter.
The uber-green zone would see existing homes retro-fitted with green technology and the house owners would be the first to receive advice from the new Green Homes Service.
Also announced was an increase in the projected number of jobs created by the Thames Gateway – Europe’s largest regeneration project – from an original figure of 180,000 to 225,000 by 2016.
The £9 billion pot will be allocated to provide more jobs, better education – including 22 new schools –an improved transport scheme and more affordable homes. The region will also gain eight new hospitals.
Housing minister Yvette Cooper said: ‘Since last year the government has secured funding for major projects that are transforming the Gateway: the new deal on Crossrail, a high-speed line to London, Paris and Brussels; and London Gateway, the biggest deepwater port in Europe.
'We have already achieved a great deal but we must raise our ambitions and go further and faster.'