The four storey 7,800 m 2postgraduate centre for tropical and infectious diseases will house laboratories as well as research and office space and has just won planning permission from Liverpool City Council.
Founded in 1898, the school was the world's first institution dedicated to tropical healthcare and the new centre will connect to the organisation's existing Victorian facilities through a glass bridge on the first floor.
The fully glazed building will also boast a double-space atrium and a 'natural stone' core.
The school has already secured £18 million of funding for the project from the Northwest Regional Development Agency and the Merseyside Objective One Programme.
School director professor Janet Hemingway said: 'The new centre is an integral part of our exciting plans to double the size of the school over the next five years.
'The school is a unique organisation - the only one capable of initiating, validating and trialling new drugs, vaccines and insecticides for current and emerging infectious diseases.'
The scheme is due to start on site in April and completion is expected in September next year.