The White City Collaborative Care Centre public-private partnership LIFT scheme is the first healthcare project of its kind to be taken on by Richard Rogers' practice.
The new building, which will sit on the site of the now-demolished Janet Adegoke Leisure Centre (pictured), will house GPs' surgeries, walk-in clinics, community nursing facilities and mental-health services.
Backed by Hammersmith & Fulham (H&F) Council, the local Primary Care NHS Trust and private funder Building Better Health, the development in Bloemfontein Road is being billed as a 'landmark building' which will create 'an integrated range of health and social-care services'.
RSH has limited previous experience of working in healthcare, although it is about to complete a Maggie's cancer care centre - also in Hammersmith - and has been earmarked for future work as part of the innovative Centres of Clinical Excellence programme.
However, councillor Antony Lillis, H&F's cabinet member for community services, is confident the firm will deliver a top-class, flexible facility. He said: 'This would be a landmark scheme providing a wide range of services from one site.
'Nearly 60 per cent of adults and older people registered with a disability live in the north of the borough, with the highest proportion in the Wormholt and White City area.
'This development will serve these and other residents and contribute to the regeneration of the White City area.'