Originally granted planning permission in June 2005, the first plans detailed building space of 280,000m2. The resubmitted proposal shows an increase of more than 45,000m2 to 327,255m2.
The scheme consists of two towers, the taller standing 241m high, making it the second tallest tower in the Canary Wharf cluster behind One Canada Square.
The towers will be linked by a lower building, which closely follows the original proposal granted planning in 2005.
A spokeswoman for the Canary Wharf Group, which owns the land, said: 'The building space has increased, not the amount of office space - the development is now 327,255m2.'
The scheme will be mixed-use, with office space in the upper floors and retail space in the ground floors.
Tower Hamlets Council is expected to make a decision on the new plans in the summer.