The competition-wining Syeton project, which will create 1,000 units on a waterfront site, was the first major announcement from MIPIM.
The practice beat finalists Erick Van Egeraat, PRP, GTL + Jochen Brandi, and Dutch firm Wonderland.
The residential elements of the scheme will vary in height from three to six storeys and, unusually for Russia, will have roof terraces and 'Corbusian-style' winter gardens.
Backed by a joint venture between the ST Group and developer Don-Stroy, the scheme is the latest in a line of big project wins for RMJM in Moscow that have seen the Scottish firm take advantage of the burgeoning Russian market.
The practice is also currently awaiting the outcome of a planning application for another Moscow scheme, which features a 50-storey tower.