The £6 million mixed-used scheme will house a range of care and education services, which are currently spread over three dilapidated sites within Southwark. There are also plans for 36 new flats to help subsidise the project.
Arranged around a double-height courtyard, the foundation building will provide a crèche, resource room, lounge and reception.
A spokesman for SEH said: 'This will be the hub of the Blackfriars Settlement, where users and staff from different services converge, meet casually and socialise.
'We hope this will help consolidate the sense of community already operating in the existing building and provide an entrance that is welcoming and accessible to all members of the community - including people of impaired vision, hearing and mobility,' he added.
If the scheme is given the go-ahead, work should begin on site in late July. The centre is set to open its doors before the end of next year.