The £80 million project will provide sports facilities, a school, residential units and retail and entertainment space across the 14ha site for Russian client Sestra River Developments.
The project presents considerable challenges, as the site is heavily contaminated, and the development must be created within a series of listed buildings.
The site was originally established in the 1720s, when Peter I, founder of St Petersburg, was the ruling emperor.
The scheme is one of several projects Paul Davis & Partners is involved with in St Petersburg, thanks to having a close working relationship with UK Trade and Investment (UKTI).
Design director and project leader Pedro Roos said: 'We are benefiting from a very productive relationship with the UKTI. Not only have they introduced us to this outstanding opportunity, we have also won some major developments in mainland China as a result of overseas delegations they have organised.'
The practice submitted the designs for planning at the end of August, and hopes to begin on site by the middle of next year.