The proposals for the site will face heavy local scrutiny, as the area is considered a key part of the cultural and urban design history of the city.
The proposal is also architecturally sensitive because of its proximity to Ralph Erskine's Byker Wall estate, one of the key examples of Modern architecture in the North East.
A spokesman for Hopper Howe Sadler said: 'Today art, music, culture, leisure, small businesses and the 'informal sector' all mix together in the Ouseburn Valley and overlap to give a degree of vibrancy.
'Although a residential community is yet to become established within the valley, stakeholders, and a number of interested parties who use the valley, fiercely protect the Ouseburn's identity.
'It was felt therefore that it would be inappropriate to rebrand the area, dominate or overpower its existing character.
'Instead, the urban-design process aims to draw out what is already there, build on and support the existing uses and work around, and with, the remaining historic built fabric,' he added.