The project aims to redevelop the university's Newton and Arkwright buildings and provide a link between them via a 'central court' and a new quadrangle.
The practice says the scheme will 'allow the existing buildings on either side to work together to provide a front door to the city-centre campus'.
The buildings will provide the university with new lecture theatres and updated teaching space for more than 4,000 students, as well as a new support centre, a conference area and restaurant facilities.
Hopkins has had sporadic forays into the education sector in the past, and this will be the second university in Nottingham the practice has been commissioned by, following its Nottingham University Jubilee Campus scheme, completed in 1999.
As yet a contractor has not been appointed, but a date for completion has been set for the start of the 2009/2010 academic year.