The Italian architect's ambitious plans include new tree-lined boulevards, a series of 'stunning' developments alongside the River Irwell and the rejuvenation of the area's historic buildings.
Masterminded by the Central Salford Urban Regeneration Company, the vision will guide the city's regeneration during the next 10 to 20 years and focuses on maximising the 'area's natural assets.'
Fuksas, who has been working on the draft proposals since November, said: 'I thought our mission was a tough one at first, but now - having seen what Salford already has to offer, I can guarantee it is possible to change in a clever, intelligent and very different way.'
He added: 'By 2025 Salford will have undergone a magnificent metamorphosis. Green boulevards will link the northern, southern and western parts of Salford, along a succession of high quality urban squares and green spaces, to the buzzing regional centre.'
Internationally renowned regeneration expert Stuart Gulliver is also working on the draft vision with Fuksas and he is only too aware of the challenges ahead.
He said: 'If we turn the first industrial city on earth into a 21st century city beautiful we will really have achieved something special.'
The project, which would revamp more than 2,100 ha of land on the western boundary of Manchester city centre, is being developed by the Northwest Regional Development Agency (NWDA), English Partnership and Salford City Council.
It is hoped the final regeneration framework will be published in autumn.