Sat on two listed buildings, Jameson House will be divided into 10 storeys of commercial space - including shops and a restaurant - and 25 storeys of apartments with underground parking.
At the top of the tower, balconies and a roof terraces are to become 'green spaces' which will be irrigated by a rainwater-harvesting system. The building will also feature Vancouver's first cogeneration plant, which will run on a bio-diesel primary fuel combined with 'absorption cooling'.
A key part of the scheme involves the restoration of the listed buildings at the base of the skyscraper.
As well as refurbishing and retaining the facade of the 1929 B-listed Chamber of Mines, there are also plans to return the A-listed 1921 Ceperley Rounsfell Building to its original 'double-height configuration'.
Leading the Jameson House team, Nigel Dancey, a senior partner in Foster and Partners, said: 'It is a unique opportunity to create a building that draws its inspiration from the historic fabric of this engaging city.
'In parallel, the scheme will inject the precinct area with a new lease of life, while offering a model for sustainable urban living.'