PRP has worked up plans for 286 homes as part of the £1.7 billion ongoing renaissance of the 28ha area in north-west London.
The building (pictured) will be built around a large courtyard, with affordable housing spread throughout the complex.
This first phase includes wheelchair-accessible housing and duplex flats for larger family accommodation.
The architect claims a number of initiatives have been incorporated into the scheme to ensure environmental sustainability. These include a combined heat and power (CHP) system and rainwater-harvesting apparatus for the roof.
The CHP system will involve a boiler that is capable of using renewable fuels to heat the whole plot.
Nick Shattock, a director at developer Quintain said: 'The development of the very first residential block at Wembley is hugely significant for us. It will set the benchmark for the plots to follow and help change perceptions of the area.'