The Newlands Common scheme, for developer Grainger, consists of 100,000m2 of commercial space spread over a 132ha site and 1,550 new homes.
The £100 million development will also include a provision for a further 1,000 residential units.
Following approval of the outline scheme, FCB has started the detailed design of the first phases, and a detailed planning application together with a design guide will be submitted later this year.
The completed development will give pedestrians priority over cars, and the developer has promised that the site's existing hedgerows, woodland and conservation meadows will be 'retained and enhanced'.
The River Wallington - which runs through the site - will also be 'de-canalised' and returned to its natural state.
A community centre, a primary school, a health centre, a pharmacy, start-up offices, a café, and a retirement village will all be included in the development.
Grainger is to create a management company for the development. Other stakeholder members of the management company will include the local authority, residents, a housing association and the Hampshire Wildlife Trust.