The 21,000m 2John Lewis store will be the focal point of Centros Miller's development of Portsmouth's Northern Quarter, which hopes to bring millions of shoppers to the coastal city.
The entire development will deliver 80 new shops, cafés and restaurants as well as more than 200 new flats and leisure facilities, with the John Lewis store sitting in the centre.
The four-storey John Lewis building is set to become the largest department store in the country when it opens, employing more than 400 people.
Lead architect Roger Wilson, of Chapman Taylor, said: 'We have harnessed the constraints of the site by composing a dynamically shaped stand-alone department-store building. The design reinforces a legible typology and essence of department store architecture whilst fulfilling its functional brief.
'It makes a significant architectural statement for the city of Portsmouth as well as for the Northern Quarter development,' he added.
The developer, Centros Miller, stated that the detailed design of the other buildings will be revealed in the coming months as the designs evolve.
The scheme is expected to be completed in autumn 2010.