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Competition: King’s College London vector manufacturing facility

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King’s College London is recruiting a design team for a new £4 million viral vector manufacturing facility on Newcomen Street

The winning team will draw up plans for a new build facility within the Guy’s Hospital complex which will produce experimental viral vectors – a key element of advanced gene therapy medicines. Designs will be expected to comply with Good Manufacturing Practice (GMP) standards.

The project – backed by the National Institute for Health Research and the Biomedical Research Centre (BRC) at Guy’s & St Thomas’ Foundation Trust – will replace an existing temporary building on Newcomen Street (pictured) a short distance from RSHP’s landmark new £160 million Cancer Centre at Guy’s Hospital.

According to the brief: ‘A viral vector development and GMP unit is required for the manufacture of recombinant lentiviral, gamma and alpha retroviral as well as adenovirus and adeno-associated virus to be used in pre-clinical and clinical trials up to but not excluding phase III.

‘Within the UK’s Advanced Therapy Medicinal Products Manufacturing community, there is a view that there is a worldwide shortage of viral vector manufacturing capacity, because the use of viral vectors in gene therapy is increasing fast. Because of the shortage and the complexity of the technology, viral vectors are very valuable products, commanding high prices in the market. Therefore, there is an unmet business opportunity to increase production within the BRC.’

King’s College London is a research-led university headquartered in Aldwych, central London, hosting more than 26,000 students and 7,000 employees.

The university works in partnership with three south London hospitals – Guy’s and St Thomas’, King’s College Hospital and South London and Maudsley NHS Foundation Trusts – to deliver teaching, research and healthcare.

The latest project, planned to complete in 2021, will redevelop the site of an existing Yorkon port-a-cabins structure on Newcomen Street just off Borough High Street.

The winning team will be expected to deliver architectural, lead designer, principle designer, and MEP consultant services.

The deadline for applications is 12noon on 7 November.

How to apply

Visit the competition website for more information

Contact details

Room 4.21
King’s College London
James Clerk Maxwell Building
57 Waterloo Road
London
SE1 8WA

Tel: +44 2078488854
Email: patrick.dunne@kcl.ac.uk

 

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