The huge development - which includes two towers over 200-metres tall - was granted planning permission by Tower Hamlets council earlier this week.
The scheme is located at North Quay on the Isle of Dogs and is comprised of the two towers with a lower building located in between. The buildings will be linked by three lower podium floors that have enhanced height to facilitate trading operations and other special tenant requirements.
Chief executive of the Canary Wharf Group George Iacobescu said: 'This significant decision continues the planning for the next generation of buildings for Canary Wharf and we are looking forward to continuing our work with the London Borough of Tower Hamlets in developing this project at this important site in the Docklands.'
Consent for the whopping 400,000m2 office and retail development is subject to the agreement of the Mayor of London and the Government Office for London.
It is also subject to the agreement of a planning condition and coordination with Cross-London Rail Links.