The competition winners and those who pick up honourable mentions will each win supplies of condoms as prizes.
The aim of the competition, which is being backed by Squire and Partners, is to generate ideas that can 'inform and inspire' architects working in Africa.
In addition, the initiative also hopes to raise cash towards the building of an AIDS orphanage in South Africa.
The competition brief demands that schemes should 'enrich the provision of facilities for AIDS orphans' through 'ingenuity, innovative use of recycled materials and the careful analysis of spatial and formal relationships'.
There will be three prize-winners, each receiving a year's supply of condoms, and several honourable mention awards, each receiving one month's supply of condoms.
An Architecture Sans Frontieres UK spokesman said: 'We know that AIDS is devastating whole communities in many parts of Africa and throughout the world.
'There is not one quick-fix solution to the difficulties that these children face as AIDS orphans, but we hope to improve their physical situation by both raising funds and focusing on how the design of their environments can be improved.'